Caspase 12 Antibodies

Antibodies that detect Caspase 12 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Caspase 12 in Mouse, Human and Rat samples. Our Caspase 12 polyclonal and... Antibodies that detect Caspase 12 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Caspase 12 in Mouse, Human and Rat samples. Our Caspase 12 polyclonal and monoclonal antibodies are developed in... Antibodies that detect Caspase 12 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Caspase 12 in Mouse, Human and Rat samples. Our Caspase 12 polyclonal and monoclonal antibodies are developed in Rabbit and Rat. Find the Caspase 12 antibody that fits your needs. Choose from 1 of 31 Caspase 12 antibodies, which have been validated in experiments with 127 publications and 50 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the... Antibodies that detect Caspase 12 can be used in several scientific applications, including Immunohistochemistry, Western Blot, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target Caspase 12 in Mouse, Human and Rat samples. Our Caspase 12 polyclonal and monoclonal antibodies are developed in Rabbit and Rat. Find the Caspase 12 antibody that fits your needs. Choose from 1 of 31 Caspase 12 antibodies, which have been validated in experiments with 127 publications and 50 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

Target Information

Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved. The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved. Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion. Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis. Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including -gamma-secretase presenilin and beta-amyloid precursor protein (APP). Caspase-12 mediates cytotoxicity induced by amyloid-beta. Caspase-12 is ubiquitously expressed in mouse tissues.

Synonyms

CASP12; CASP-12; CASP12P1; caspase 12; caspase 12 (gene/pseudogene); caspase 12 pseudogene 1; caspase-12; Inactive caspase-12; OTTMUSP00000045799; OTTMUSP00000045802; OTTMUSP00000045803; UNQ9415; UNQ9415/PRO34398

Caspase 12 Antibodies

Target Information

Synonyms

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